In the production of solid preparation tablets, mixing and granulation are the key factors to determine the quality of tablets or capsules. In a sense, granulation is the key basis.Past industry integrity grain use more is the wet legal system grain of equipment, and the wet legal system grain of equipment has grown to high-speed mixing system grain of machine, it is developing fast in recent years a solid preparation pharmaceutical equipment, the mixing, granulating two-step process together, which saves time and meet the requirement of GMP, reduce the cross contamination, improve the efficiency, is popular among users.
It is supported by the fuselage as a pot for feeder, stirring rotation and cutting transmission power, with stirring impeller material, the material in a short time, mixing, by cutting again fly knife made from grain, and then from the discharging mouth out, change the mixing and cutting speed, the particles of different size of equipment is achieved.
The high speed mixed granulator adopts horizontal cylinder structure, which is reasonable in structure.Pneumatic seal drive shaft, can be changed to water when cleaning.Fluidized granulation, granulation approximate spherical, good fluidity.Compared with the traditional process of 25% less adhesive, drying time is shortened.Each batch is dry mixed for 2 minutes and granulated for 1-4 minutes, which is 4-5 times more efficient than the traditional process.Completed in the same closed container, dry mixing - wet mixing - granulation, process reduction, in line with GMP specifications, the whole operation also has strict safety protection measures.
High-speed mixed granulator is very convenient to use, but the heat loss in use has been relatively large, so we should take corresponding measures to reduce related consumption, which can not only improve work efficiency, but also increase the overall economic benefits.According to the introduction of the industry, generally reduce heat loss to avoid high speed hybrid granulator overload and optimize heat transfer two ways, but the more effective method is to strictly control the fuel air ratio, operating close to the fuel air ratio, but also to control fuel consumption.It can also be maintained with existing control equipment. The main operations are as follows:
1. Direct heat recovery products.If the exhaust gas leaving the hot part can enter the relatively cold feed load, the energy will be transferred to the preheating load, which reduces the energy discharged by the exhaust pipe, which can effectively utilize the waste heat in the exhaust.
2. Use waste heat recovery to preheat combustion air.This is commonly used in medium-high temperature industrial furnaces, where burners that use preheated air reduce the amount of fuel needed to purchase to meet process heat requirements, and preheated combustion air requires a heat exchanger or recycling.
3. Waste heat boiler.Boiling pelletizer manufacturers introduced the use of waste heat boilers to recover some of the heat from the exhaust as an option that requires steam or hot water.